Neurology: A Queen Square Textbook by Charles Clarke, Robin Howard, Martin Rossor, Simon Shorvon PDF

By Charles Clarke, Robin Howard, Martin Rossor, Simon Shorvon

ISBN-10: 111848617X

ISBN-13: 9781118486177

Neurology: A Queen sq. Textbook, moment variation, is a completely revised and up-to-date spouse that demonstrates the fast speed of development inside of medical neurology and utilized neurosciences 

  • A entire and useful evaluation of present advancements inside scientific neurology, synthesising medical neurology with translational research 
  • Expertly edited and written by means of neurologists, neuroscientists and neurosurgeons operating at Queen sq., instructed by way of an uncommon foreign Editor crew to give a world perspective 
  • Introductory chapters summarise the elemental sciences underpinning the perform of medical neurology, together with genetics, channelopathies, immunology, neurophysiology and neuropathology
  • All chapters absolutely revised and up to date to mirror the expanding position of neurologists in acute care
  • Includes new contributions touching on significant advancements within the care of; stroke, epilepsy, dementia, Parkinson's illness, a number of sclerosis, neuromuscular disorder, headache, infections, spinal illness, cranial nerve ailment, neuropsychiatry, neurogenetics, neuro-oncology, uroneurology, neuro-otology, neuro-ophthalmology, soreness medication, sleep medication, metabolic sickness, medicines and pollutants, autonomic disorder, systemic ailment, and neurorehabilitationfor dementia, epilepsy, complications, neuro-genetics and lots of more

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Read e-book online Neurology: A Queen Square Textbook PDF

Neurology: A Queen sq. Textbook, moment variation, is an absolutely revised and up-to-date better half that demonstrates the swift speed of development inside of medical neurology and utilized neurosciences  A entire and useful evaluate of present advancements inside of medical neurology, synthesising medical neurology with translational study  Expertly edited and written by means of neurologists, neuroscientists and neurosurgeons operating at Queen sq., instructed by means of an unique foreign Editor workforce to give an international standpoint  Introductory chapters summarise the elemental sciences underpinning the perform of medical neurology, together with genetics, channelopathies, immunology, neurophysiology and neuropathology All chapters totally revised and up to date to mirror the expanding position of neurologists in acute care comprises new contributions touching on significant advancements within the care of; stroke, epilepsy, dementia, Parkinson's affliction, a number of sclerosis, neuromuscular sickness, headache, infections, spinal illness, cranial nerve ailment, neuropsychiatry, neurogenetics, neuro-oncology, uroneurology, neuro-otology, neuro-ophthalmology, discomfort drugs, sleep medication, metabolic disorder, medicines and pollutants, autonomic illness, systemic sickness, and neurorehabilitationfor dementia, epilepsy, complications, neuro-genetics and lots of extra

Additional resources for Neurology: A Queen Square Textbook

Example text

Those that affect the axon itself), and demyelinating, where the intregrity of myelin is compromised. Myelin was a word coined by Virchow, simply for a fatty s­ ubstance obtained from various tissues; it was adopted by Schwann to describe the ‘white substance’ of peripheral nerves. CNS myelin provides similar conduction properties, but there are specific neu‑ rochemical characteristics that differentiate it from peripheral nerve myelin. Some functional features of peripheral nerve myelin are outlined here: • Rapid conduction along both peripheral nerves and within the CNS is achieved by saltatory conduction.

Motor loops Several neuronal servo‐loops commence and end in the motor and frontal areas of the cerebral cortex. They all involve cortical projections to the striatum (putamen + caudate nucleus) and return p ­ rojections to the cortex via the thalamus. Within each loop there exist two interrelated motor pathways: direct and indi‑ rect pathways. Transmission through the loops is controlled by activity in the nigrostriatal pathway, from the pars compacta of the substantia nigra to the lateral globus pallidus, where axons make two principal types of synapse, on excitatory D1 (dopaminergic, direct pathway) and inhibitory D2 (indirect pathway) receptors.

It is also frequently impossible to attribute a specific symptom or physical sign to a single structure. In other words (cf. the cerebral cortex), individual diseases do not appear to affect one discrete area, and thus localisation of one function to a particular zone is often not possible. There was a relative paucity of interest in disorders of movement until the second half of the twentieth century. Advances in knowl‑ edge of the functions of neurotransmitters, levodopa therapy, stere‑ otactic surgery, deep brain stimulation and fMRI and have brought a different focus to this field, which continues to expand rapidly.

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Neurology: A Queen Square Textbook by Charles Clarke, Robin Howard, Martin Rossor, Simon Shorvon


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